Alzheimers Disease How It Affects The Cells Article
Alzheimers Disease
By Steven Godlewski
Alzheimers disease robs you of intellectual and social abilities and interferes with regular life. About 4.5 million Americans have Alzheimers
Disease. The disease usually affects seniors over the age of 65. As the population ages this number is expected to quadruple. There is no cure for
Alzheimers disease. There is progress being made by researchers to improve the quality of life for those who have Alzheimers. Drugs are being discovered and
studied which may lead to treatments of the disease. If you have been a caretaker of a loved one with Alzheimers disease, or have a loved one suffering with
it, you know that it takes patience and love to keep you and them going. If you think a loved one may be showing early signs of Alzheimers Disease, what
should you look for? One of the most prominent signs of Alzheimers Disease is forgetfulness. It starts out with occasional forgetting simple directions or recent events.
It progressively gets worse until the patient may forget even family names and objects they see every day. They also may repeat things they've already told someone,
and put objects down and forget where they placed them. On the other hand, they might put something away so they will remember where they put it, and put it in
such an illogical place that no one can find it. Early Alzheimers Disease patients have trouble conducting conversation and finding the right words to say.
They may have a hard time following conversations or expressing their feelings. Eventually their reading and writing ability will also be affected. Abstract
thinking is something else that these patients with Alzheimers disease have. They may suddenly be able to deal with numbers, especially in balancing the
checkbook. Disorientation causes them to lose track of time, and it is easier for them to get lost. They may feel they are in unfamiliar surroundings even if they are
home. They have trouble with everyday problems, such as knowing that food has been on the stove too long. Patients with Alzheimers disease eventually
have problems dealing with planning, judgment, and decision-making. Familiar tasks become a struggle, even the basic activities like dressing or remembering to
bathe. One of the most distressing symptoms of Alzheimers disease is the personality changes that affect them. It is not uncommon for a patient with
Alzheimers disease to have extreme mood swings and often accompanied by depression. They may begin distrusting those around them, be increasingly stubborn,
and withdraw from family and friends. As their Alzheimers disease get progressively worse, they may become defiant, stubborn, aggressive, and take part in
inappropriate behavior. One report tells of a wonderful woman, whom was a good mother, grandmother, and great-grandmother that had been afflicted with
Alzheimers disease. When her family was forced to put her in a nursing home due to the Alzheimers disease, she became aggressive to other patients and began
using language she never would have dreamed of using before she fell victim to Alzheimers disease. The staff had a hard time in restraining her in the nursing home.
They found she was sneaking in to other patient's rooms, uncovering them, and leaving them. This was so unlike the mother and grandmother they knew before the
affliction of Alzheimers disease, they had a hard time even visiting. Most of the time, she wouldn't remember her daughter being there that morning. Finally, her family
put an erasable board in her room so her visitors could write their name and the date they visited allowing the family to know who was there and
when. Unfortunately, families don't often recognize the onset of Alzheimers disease because it starts out so slow. There usually are no sudden changes in the
personality to alert family members there is a problem. As the symptoms gradually get worse, or they realize memory is fleeting for their loved one, they may not realize
until the patient is far into the advanced stages of Alzheimers disease. How Alzheimers disease progresses and what the average survival rate will be
depends on the individual. The average survival rate is eight years. Some live fewer years, and some could live up to 20 years with the disease. People with
Alzheimers disease eventually will no longer be able to take care of themselves. This leaves loved ones with the burden of deciding whether to place the patient in a
long-term care facility or try to take care of them at home. It's a difficult decision and everyone must realize that it takes considerable attention, love, and patience to
deal with the problems that come with Alzheimers disease.
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14 Apr 2008 at 6:00pm DXY voa special english 20 3 min - Apr 14, 2008 This is the *** Special English Health Report. Being overweight can lead to high blood pressure, diabetes and heart attacks. But now there may be another reason to lose the fat, especially around the middle of the body. A recent study suggested that people in their forties with belly fat have an increased risk of dementia later in life. Dementia is the name for a group of brain disorders that affect memory, behavior, learning and language. Alzheimer's disease is the most common cause. Dementia rarely appears before the age of sixty. The new study added to growing evidence that people with large stomachs can face greater health risks than others who are overweight. The study involved more than six thousand northern California members of Kaiser Permanente, a health care organization. Researchers looked at the patients' medical records from between nineteen sixty-four and nineteen seventy-three. The people were in their early to mid-forties at the time. They were all part of a long-term health study that included measurements of belly fat. The researchers compared the records with those from when the patients were in their seventies. By that time, almost one out of six of them had dementia. The researchers found that dementia was more common in those with wider bellies. Those with the highest belly measurements had almost three times the risk of dementia compared to those with the lowest. Belly size appeared to make a difference even in patients with normal body weight. Belly size is linked to a kind of fat that grows around organs and produces harmful substances. Experts believe that belly fat is more dangerous than other kinds of fat cells that grow just under the skin. The researchers say this is the first study to demonstrate a link between midlife belly fat and the risk of dementia. Still, it is possible that this apparent connection could be the result of a complex set of health-related behaviors. The findings appeared in the journal Neurology. Rachel Whitmer from the Kaiser Permanente research division led the study. She says the findings do not explain why belly fat may be linked to dementia. But she says the study should send a warning. Other research has shown that brain changes linked to Alzheimer?s disease might begin as early as young adulthood. And another stu ??????? ed that belly fat in old people was tied to increased loss of brain cells. And that?s the *** Special English Health Report, written by Caty Weaver. I?m Barbara Klein. Read more...
11 Mar 2008 at 8:42am Marijuana/Cannabis memory loss & Alzheimer'sst0ckman 2 min - Mar 11, 2008http://st0ckman.blogspot.com The active ingredient in marijuana may stall decline from Alzheimer's disease, research suggests. Scientists showed a synthetic version of the compound may reduce inflammation associated with Alzheimer's and thus help to prevent mental decline. They hope the cannabinoid may be used to developed new drug therapies. The research, by Madrid's Complutense University and the Cajal Institute, is published in the Journal of Neuroscience. We would warn the public against taking marijuana as a way of preventing Alzheimer's Dr Susanne Sorensen The scientists first compared the brain tissue of patients who died from Alzheimer's disease with that of healthy people who had died at a similar age. They looked closely at brain cell receptors to which cannabinoids bind, allowing their effects to be felt. They also studied structures called microglia, which activate the brain's immune response. Microglia collect near the plaque deposits associated with Alzheimer's disease and, when active, cause inflammation. The researchers found a dramatically reduced functioning of cannabinoid receptors in diseased brain tissue. This was an indication that patients had lost the capacity to experience cannabinoids' protective effects. The next step was to test the effect of cannabinoids on rats injected with the amyloid protein that forms Alzheimer's plaques. Those animals who were also given a dose of a cannabinoid performed much better in tests of their mental functioning. The researchers found that the presence of amyloid protein in the rats' brains activated immune cells. However, rats that also received the cannabinoid showed no sign of microglia activation. Using cell cultures, the researchers confirmed that cannabinoids counteracted the activation of microglia and thus reduced inflammation. Read more...
25 Feb 2008 at 5:00am Neil Cherry Radio Show Part 2 Cell Phone Tower Controversiesbreatheasy7000 10 min - Feb 25, 2008http://www.emfnews.org Cell Phone Towers: dangerous or not? If you ask the government, no studies have shown conclusive evidence that radio-frequency emissions, a form of electromagnetic radiation (EMR), from cell towers are harmful. According to the Food and Drug Administration: "RF [Radio frequency] exposure on the ground is much less than exposure very close to the antenna and in the path of the transmitted radio signal. In fact, ground-level exposure from such antennas is typically thousands of times less than the exposure levels recommended as safe by expert organizations. So exposure to nearby residents would be well within safety margins." Cell phone companies also maintain that no risks exist from the towers. "There are no health risks posed by the towers. Independent scientific panels around the world have reached this conclusion," said Russ Stromberg, senior manager of development at T-Mobile. But other studies seem to tell a different story, with findings such as: ? A study by Dr. Bruce Hocking in Australia found that children living near three TV and FM broadcast towers (similar to cell towers) in Sydney had more than twice the rate of leukemia than children living more than seven miles away. ? Says Dr. Neil Cherry, a biophysicist at Lincoln University in New Zealand: o "Public health surveys of people living in the vicinity of cell site base stations should be being carried out now, and continue progressively over the next two decades. This is because prompt effects such as miscarriage, cardiac disruption, sleep disturbance and chronic fatigue could well be early indicators of the adverse health effects. Symptoms of reduced immune system competence, cardiac problems, especially of the arrhythmic type, and cancers, especially brain tumor and leukemia, are probable." ? Biomedical engineer Mariana Alves-Pereira has said "From what I understand, some of the complaints are similar in what is seen in vibroacoustic disease patients, which are people who develop a disease caused by low frequency noise exposure," she said. Symptoms can include mood swings, indigestion, ulcers and joint pain. ? Dr. Gerard Hyland, a physicist who was nominated twice for the Nobel Prize in medicine, says, "Existing safety guidelines for cell phone towers are completely inadequate ... Quite justifiably, the public remains skeptical of attempts by governments and industry to reassure them that all is well, particularly given the unethical way in which they often operate symbiotically so as to promote their own vested interests." ? According to the Mount Shasta Bioregional Ecology Center, "Studies have shown that even at low levels of this radiation, there is evidence of damage to cell tissue and DNA, and it has been linked to brain tumors, cancer, suppressed immune function, depression, miscarriage, Alzheimer's disease, and numerous other serious illnesses." ? According to Dr. W. Löscher of the Institute of Pharmacology, Toxicology and Pharmacy of the Veterinary School of Hannover in Germany, dairy cows that were kept in close proximity to a TV and cell phone tower for two years had a reduction in milk production along with increased health problems and behavioral abnormalities. In an experiment, one cow with abnormal behavior was taken away from the antenna and the behavior subsided within five days. When the cow was brought back near the antenna, the symptoms returned. http://www.neilcherry.com Read more...
17 Feb 2008 at 3:30pm Niemann-Pick Disease, What is It? Why is it a Child Killer?gabrielle824 4 min - Feb 17, 2008http://www.GabrielleLaVerde.com See Gabrielle on Fox 35: http://www.myfoxorlando.com/myfox/pages/Home/Detail;jsessionid=C0A93F018E2AF589C52619ECD6C09AF9?contentId=5916783&version=1&locale=EN-US&layoutCode=VSTY&pageId=1.1.1&sflg=1 What do we know about Niemann-Pick Disease (NPD) and Types A, B, and C. There is even a Type D which is closely related to Type C. The Name Niemann-Pick derives from two German Pediatricians. Albert Niemann, the first doctor to identify Type A in 1914, and Ludwick Pick, who first identified Type B in 1927. Niemann-Pick Disease (NPD) is closely related to Alzheimer's Disease. and is often called The Childhood Alzheimer's. Patients with NPD Type C are not able to metabolize cholesterol properly in lysosomes. Consequently, excessive amounts of cholesterol accumulate within the liver, spleen, and brain. Signs and Symptoms of Type A may include: feeding difficulties, large abdomen within 3-6 months, a loss of early motor skills, and a rapid decline in the child after 6 months, leading to death by 2 to 3 years of age. In Contrast, the severity and onset of Type B is very variable. Some patients with Type B develop repeated respiratory infections & breathing problems. Life Expectancy of Type B is highly variable, depending on the severity of the symptoms. Type C NPD usually affects children of school age but the disease can strike at any time from early infancy to adulthood. Symptoms of NPD Type C may include jaundice, a large spleen and/or liver, difficulty with upward and downward eye movement. Other symptoms include: clumsiness, and problems in walking, controlling limb movement, slurred or irregular speech, learning difficulties, inability to swallow, and other neurological abnormalities. Life Expectancy of Type C NPD is variable depending on the severity of the symptoms. However, life expectancy after diagnosis is merely 6 - 10 years. Children seldom survive beyond their 15th birthday. With the discovery in 1997 of the primary gene associated with NPD-C, medical research has intensified worldwide. Ara Parseghian, former head coach for University of Notre Dame, inducted into the College Football Hall of Fame in 1980, lost his three grandchildren to NPD Type C. his Grandson, Michael, his Granddaughter, Christa, who passed away at the age of 10 in October 2001, and his Granddaughter Marcia, who passed away at the age of 16, in 2005. NPD is considered an important link in the battles against heart disease, Alzheimer's, stroke and seizure disorders. Join us, in finding a cure for NPD, and Help us Save Gabrielle LaVerde, a first grade student diagnosed with NPD Type C in October, 2007. Read more...
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